Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1276949 |
| description: |
epitope description:RLLSTFTEYIKNIINTSILNLRYESNHLIDLSRYASKINIGSKVNFDPIDKNQIQLFNLESSKIEVILKNAIVYNSMYENFSTSFWIRIPKYFNSISLNNEYTIINCMENNSGWKVSLNYGEIIWTLQDTQEIKQRVVFKYSQMINISDYINRWIFVTITNNRLNNSKIYINGRLIDQKPISNLGNIHASNNIMFKLDGCRDTHRYIWIKYFNLFDKELNEKEIKDLYDNQSNSGILKDFWGDYLQYDKPYYMLNLYDPNKYVDVNNVGIRGYMYLKGPRGSVMTTNIYLNSSLYRGTKFIIKKYASGNKDNIVRNNDRVYINVVVKNKEYRLATNASQAGVEKILSALEIPDVGNLSQVVVMKSKNDQGITNKCKMNLQDNNGNDIGFIGFHQFNNIAKLVASNWYNRQIERSSRTLGCSWEFIPVDDGWGERPL
antigen name:Botulinum neurotoxin type A (UniProt:A5HZZ9)
host organism:Mus musculus BALB/c
antibody name:S25
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
9284147 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1001433 |
| landingPage: |
http://www.iedb.org/assay/1276949 |
| type: |
Literature
|
| publicationVenue: |
Infect Immun
|
| dates: |
1997
|
| study type: | b cell assays |
| subject species: | Clostridium botulinum |
| fullName: |
P Amersdorfer
C Wong
S Chen
S Deshpande
R Sheridan
R Finnern
J D Marks
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Molecular characterization of murine humoral immune response to botulinum neurotoxin type A binding domain as assessed by using phage antibody libraries.
|
| description: |
Affinity for the whole toxin was determined for a purified sc-Fv fragment selected from a phage display library constructed with the VH and VL cDNAs from a mice immunized with the Hc (receptor-binding) domain of BoNT/A followed by a boost with the holotoxin. This scFv was shown to bind Hc domain in ELISA and to have neutralizing activity of the holotoxin in an in vitro mouse hemidiafragm assay.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
