Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1277837 |
| description: |
epitope description:KNIINTSILNLRYESNHLIDLSRYASKINIGSKVNFDPIDKNQIQLFNLESSKIEVILKNAIVYNSMYENFSTSFWIRIPKYFNSISLNNEYTIINCMENNSGWKVSLNYGEIIWTLQDTQEIKQRVVFKYSQMINISDYINRWIFVTITNNRLNNSKIYINGRLIDQKPISNLGNIHASNNIMFKLDGCRDTHRYIWIKYFNLFDKELNEKEIKDLYDNQSNSGILKDFWGDYLQYDKPYYMLNLYDPNKYVDVNNVGIRGYMYLKGPRGSVMTTNIYLNSSLYRGTKFIIKKYASGNKDNIVRNNDRVYINVVVKNKEYRLATNASQAGVEKILSALEIPDVGNLSQVVVMKSKNDQGITNKCKMNLQDNNGNDIGFIGFHQFNNIAKLVASNWYNRQIERSSRTLGCSWEFIPVDDGWGERPL
antigen name:Botulinum neurotoxin type A (UniProt:A5HZZ9)
host organism:Oryctolagus cuniculus New Zealand White
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| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
16177380 |
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1001122 |
| landingPage: |
http://www.iedb.org/assay/1277837 |
| type: |
Literature
|
| publicationVenue: |
Infect Immun
|
| dates: |
2005
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| study type: | b cell assays |
| subject species: | Clostridium botulinum A str. Hall |
| fullName: |
Michael R Baldwin
William H Tepp
Christina L Pier
Marite Bradshaw
Mengfei Ho
Brenda A Wilson
Robert B Fritz
Eric A Johnson
Joseph T Barbieri
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| method: |
biological activity
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| name: |
Characterization of the antibody response to the receptor binding domain of botulinum neurotoxin serotypes A and E.
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| description: |
This fragment is stated to include the complete Hc domain of BoNT/A1. Other references cite the domain as starting at residue 860.
BoNT/A1 toxin (700,000 LD50) lethality in mice is inhibited by preincubation with rabbit antisera raised to its Hc domain. However, no neutralization of BoNT/E could be afforded by this antisera.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
