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Title: Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.
identifier: 1277850
description:
epitope description:QLINTNGSWHIN
antigen name:Genome polyprotein
host organism:Mus musculus BALB/c
antibody name:AP33
aggregation:
instance of dataset
availability:
available
primaryPublications: 16496330
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001654
landingPage: http://www.iedb.org/assay/1277850
type:
Literature
publicationVenue:
Hepatology
dates:
2006
study type: b cell assays
subject species: Hepatitis C virus (isolate Glasgow)
fullName:
Alexander W Tarr
Ania M Owsianka
Judith M Timms
C Patrick McClure
Richard J P Brown
Timothy P Hickling
Thomas Pietschmann
Ralf Bartenschlager
Arvind H Patel
Jonathan K Ball
method:
biological activity
name:
Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.
description:
The mouse monoclonal antibody AP33 inhibited the entry of HCV psuedoparticles (reconstituted with E1E2 proteins from various HCV genotypes: 1a, 1b, 2a, 2b, 3, 4 and 6) into cells and reduced the infectivity of HCV JFH-1.

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