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identifier: 1277860
description:
epitope description:KNIINTSILNLRYESNHLIDLSRYASKINIGSKVNFDPIDKNQIQLFNLESSKIEVILKNAIVYNSMYENFSTSFWIRIPKYFNSISLNNEYTIINCMENNSGWKVSLNYGEIIWTLQDTQEIKQRVVFKYSQMINISDYINRWIFVTITNNRLNNSKIYINGRLIDQKPISNLGNIHASNNIMFKLDGCRDTHRYIWIKYFNLFDKELNEKEIKDLYDNQSNSGILKDFWGDYLQYDKPYYMLNLYDPNKYVDVNNVGIRGYMYLKGPRGSVMTTNIYLNSSLYRGTKFIIKKYASGNKDNIVRNNDRVYINVVVKNKEYRLATNASQAGVEKILSALEIPDVGNLSQVVVMKSKNDQGITNKCKMNLQDNNGNDIGFIGFHQFNNIAKLVASNWYNRQIERSSRTLGCSWEFIPVDDGWGERPL
antigen name:Botulinum neurotoxin type A (UniProt:A5HZZ9)
host organism:Oryctolagus cuniculus New Zealand White
aggregation:
instance of dataset
availability:
available
primaryPublications: 16177380
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001122
landingPage: http://www.iedb.org/assay/1277860
type:
Literature
publicationVenue:
Infect Immun
dates:
2005
study type: b cell assays
subject species: Clostridium botulinum A str. Hall
fullName:
Michael R Baldwin
William H Tepp
Christina L Pier
Marite Bradshaw
Mengfei Ho
Brenda A Wilson
Robert B Fritz
Eric A Johnson
Joseph T Barbieri
method:
western blot
name:
Characterization of the antibody response to the receptor binding domain of botulinum neurotoxin serotypes A and E.
description:
This fragment is stated to include the complete Hc domain of BoNT/A1. Other references cite the domain as starting at residue 860.
BoNT/A1, A2 and E HC domains are recognized by rabbit antisera raised to this domain in both WB and direct ELISA, but the titer of recognition of BoNT/E is ~5 fold lower than the titer against A-type fragments.

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