Characterization of a conserved helper-T-cell epitope from group A Streptococcal M proteins. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Characterization of a conserved helper-T-cell epitope from group A Streptococcal M proteins.

Dataset

identifier:	1278233
description:	epitope description:EAKKQVEKALEE antigen name:UniProt:A2RGM0 host organism:Mus musculus BALB/c antibody name:anti 300-319
aggregation:	instance of dataset
availability:	available
primaryPublications:	7679372

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001680
landingPage:	http://www.iedb.org/assay/1278233

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	1993

Dimension

study type:	b cell assays
subject species:	Streptococcus pyogenes str. Manfredo

Person

fullName:	J H Robinson M C Case M A Kehoe

Data Type

method:	ELISA

Study

name:	Characterization of a conserved helper-T-cell epitope from group A Streptococcal M proteins.
description:	The antibody epitope within M5[300-319] was mapped by using peptides synthesized on pins. Anti 300-319 serum bound to epitope but not to sM5[300-312] or sM5[308-319]. This indicates that peptide M5[300-319] contains a helper-T-cell epitope which can augment the antibody response to a B cell epitope in the same peptide.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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