Use of Peptide library screening to detect a previously unknown linear diagnostic epitope: proof of principle by use of lyme disease sera.

Title:

Use of Peptide library screening to detect a previously unknown linear diagnostic epitope: proof of principle by use of lyme disease sera.

identifier:	1278646
description:	epitope description:GNNSVSKEKPPSLNWPP host organism:Homo sapiens antibody name:patient serum
aggregation:	instance of dataset
availability:	available
primaryPublications:	16002626

study type:	b cell assays
subject species:

fullName:	Carl V Hamby Marta Llibre Sandeepa Utpat Gary P Wormser

method:	phage display

name:	Use of Peptide library screening to detect a previously unknown linear diagnostic epitope: proof of principle by use of lyme disease sera.
description:	One of 4 patient sera reacted postively with the epitope. Sera from two control patients (0 of 5) with rheumatoid or psoriatic arthritis were negative. The same reactivity pattern was obtained with the phage-displayed epitope and a synthetic peptide epitope.

name:	iedb
homePage:	http://www.iedb.org

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