Characterization of three novel monoclonal antibodies against hepatitis C virus core protein. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Characterization of three novel monoclonal antibodies against hepatitis C virus core protein.

Dataset

identifier:	1278948
description:	epitope description:DVKFPGGGQIVGGVYLLPRR antigen name:Genome polyprotein host organism:Mus musculus BALB/c antibody name:C7-50, C8-59
aggregation:	instance of dataset
availability:	available
primaryPublications:	8801283

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001736
landingPage:	http://www.iedb.org/assay/1278948

Publication

type:	Literature
publicationVenue:	J Med Virol
dates:	1996

Dimension

study type:	b cell assays
subject species:	Hepatitis C virus

Person

fullName:	D Moradpour K Tokushige R I Carlson K Krawczynski J R Wands

Data Type

method:	radio immuno assay (RIA)

Study

name:	Characterization of three novel monoclonal antibodies against hepatitis C virus core protein.
description:	Epitope mapping was performed with the monoclonal antibodies with a series of overlapping 20-mer peptides covering the entire HCV core region. Inhibition experiments, in which wells were coated with HCV core-GST fusion protein followed by simultaneous incubation with with radiolabeled antibody and peptide, confirmed these results.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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