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Title: Human linear B-cell epitopes encoded by the hepatitis E virus include determinants in the RNA-dependent RNA polymerase.
identifier: 1279596
description:
epitope description:ETCSRLGTAA + ACET(E1)
antigen name:Non-structural polyprotein pORF1
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 1373890
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001461
landingPage: http://www.iedb.org/assay/1279596
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
1992
study type: b cell assays
subject species: Hepatitis E virus
fullName:
M Kaur
K C Hyams
M A Purdy
K Krawczynski
W M Ching
K E Fry
G R Reyes
D W Bradley
M Carl
method:
ELISA
name:
Human linear B-cell epitopes encoded by the hepatitis E virus include determinants in the RNA-dependent RNA polymerase.
description:
N-terminal amino group was acetylated.
Serum samples from 11 Sudanese pediatric patients with acute hepatitis E diagnosed by Western blot assay were pooled and tested. The optical density (anti-IgG and IgM) which was 3-fold higher than that of pooled control sera from non-acute hepatitis E patients was selected as positive. The epitope was re-assembled with at least two adjacent 10-mer peptides that were considered positive.

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