HCV core immunodominant region analysis using mouse monoclonal antibodies and human sera: characterization of major epitopes useful for antigen detection.

Title:

HCV core immunodominant region analysis using mouse monoclonal antibodies and human sera: characterization of major epitopes useful for antigen detection.

Dataset

identifier:	1279788
description:	epitope description:PGYPWPLY antigen name:Genome polyprotein host organism:Homo sapiens antibody name:human serum
aggregation:	instance of dataset
availability:	available
primaryPublications:	9829633

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001723
landingPage:	http://www.iedb.org/assay/1279788

Publication

type:	Literature
publicationVenue:	J Med Virol
dates:	1998

Dimension

study type:	b cell assays
subject species:	Hepatitis C virus

Person

fullName:	C Jolivet-Reynaud P Dalbon F Viola S Yvon G Paranhos-Baccala N Piga L Bridon M A Trabaud N Battail G Sibai M Jolivet

Data Type

method:	ELISA

Study

name:	HCV core immunodominant region analysis using mouse monoclonal antibodies and human sera: characterization of major epitopes useful for antigen detection.
description:	The epitope was recognized by a pool of human sera positive for anti-HCV core protein. The strongest human antibody binding was obtained with peptides spanning residues 73-86, which overlapped with some peptides recognized by mouse MAbs but did not overalp with the optimal peptide.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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