Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1281805 |
| description: |
epitope description:ALNDLCIKVNNWDLFFSPSEDNFTNDLNKGEEITSDTNIEAAEENISLDLIQQYYLTFNFDNEPENISIENLSSDIIGQLELMPNIERFPNGKKYELDKYTMFHYLRAQEFEHGKSRIALTNSVNEALLNPSRVYTFFSSDYVKKVNKATEAAMFLGWVEQLVYDFTDETSEVSTTDKIADITIIIPYIGPALNIGNMLYKDDFVGALIFSGAVILLEFIPEIAIPVLGTFALVSYIANKVLTVQTIDNALSKRNEKWDEVYKYIVTNWLAKVNTQIDLIRKKMKEALENQAEATKAIINYQYNQYTEEEKNNINFNIDDLSSKLNESINKAMININKFLNQCSVSYLMNSMIPYGVKRLEDFDASLKDALLKYIYDNRGTLIGQVDRLKDKVNNTLSTDIPFQLSKYVDNQ
antigen name:Botulinum neurotoxin type A (UniProt:A5HZZ9)
host organism:Mus musculus
antibody name:9D8
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
16113261 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1001646 |
| landingPage: |
http://www.iedb.org/assay/1281805 |
| type: |
Literature
|
| publicationVenue: |
Infect Immun
|
| dates: |
2005
|
| study type: | b cell assays |
| subject species: | Clostridium botulinum A str. Hall hyper |
| fullName: |
T J Smith
J Lou
I N Geren
C M Forsyth
R
S L Laporte
W H Tepp
M Bradshaw
E A Johnson
L A Smith
J D Marks
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralization.
|
| description: |
KALNDLCIKVNNWDLFFSPSEDNFTNDLNKGEEITSDTNIEAAEENISLDLIQQYYLTFNFDNEPENISIENLSSDIIGQLELMPNIERFPNGKKYELDKYTMFHYLRAQEFEHGKSRIALTNSVNEALLNPSRVYTFFSSDYVKKVNKATEAAMFLGWVEQLVYDFTDETSEVSTTDKIADITIIIPYIGPALNIGNMLYKDDFVGALIFSGAVILLEFIPEIAIPVLGTFALVSYIANKVLTVQTIDNALSKRNEKWDEVYKYIVTNWLAKVNTQIDLIRKKMKEALENQAEATKAIINYQYNQYTEEEKNNINFNIDDLSSKLNESINKAMININKFLNQCSVSYLMNSMIPYGVKRLEDFDASLKDALLKYIYDNRGTLIGQVDRLKDKVNNTLSTDIPFQLSKYVDN The epitopic region is from the BoNT/A1 HN (translocation) domain of heavy chain.
A monoclonal antibody previously shown to be specific for the epitopic region bound botulinum neurotoxin A2.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
