Antigenic regions within the hepatitis C virus envelope 1 and non-structural proteins: identification of an IgG3-restricted recognition site with the envelope 1 protein.

Title:

Antigenic regions within the hepatitis C virus envelope 1 and non-structural proteins: identification of an IgG3-restricted recognition site with the envelope 1 protein.

Dataset

identifier:	1281821
description:	epitope description:IIPDREVLYREFDEMEEC antigen name:Genome polyprotein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	7680297

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001795
landingPage:	http://www.iedb.org/assay/1281821

Publication

type:	Literature
publicationVenue:	Clin Exp Immunol
dates:	1993

Dimension

study type:	b cell assays
subject species:	Hepatitis C virus (isolate 1)

Person

fullName:	M Sä llberg U Rudé n B Wahren L O Magnius

Data Type

method:	ELISA

Study

name:	Antigenic regions within the hepatitis C virus envelope 1 and non-structural proteins: identification of an IgG3-restricted recognition site with the envelope 1 protein.
description:	Thirty-four overlapping 18mer peptides were synthesized based on the entire sequence of the E1, E2/NS1, NS1 AND NS4 proteins of Hepatits C virus (US clone). The relative reactivity of IgG subclass with HCV-specific peptides was measured using immune sera. Seven of the 14 sera tested reacted with this NS4 peptide. IgG1 was the predominant subclass.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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