Bacterial cell surface display for epitope mapping of hepatitis C virus core antigen. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Bacterial cell surface display for epitope mapping of hepatitis C virus core antigen.

Dataset

identifier:	1281848
description:	epitope description:MSTNPKPQRKTKRNTNRRPQDVKFPG antigen name:Genome polyprotein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	14553932

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001763
landingPage:	http://www.iedb.org/assay/1281848

Publication

type:	Literature
publicationVenue:	FEMS Microbiol Lett
dates:	2003

Dimension

study type:	b cell assays
subject species:	Hepatitis C virus

Person

fullName:	Su-Min Kang Jin-Kyu Rhee Eui-Joong Kim Kwang-Hyub Han Jong-Won Oh

Data Type

method:	western blot

Study

name:	Bacterial cell surface display for epitope mapping of hepatitis C virus core antigen.
description:	Sera from patients (up to 10, representing infections with HCV genotypes 1b, 2a and 2c) reacted positively with peptides that contain the epitope. The epitope was elucidated by western blot of overlapping peptides, and only those which contained the epitope were positive. Similar results were obtained in ELISA and FACS analyses. INC, the epitope carrier is the Pseudomonas syringae ice nucleation protein (INP) with a deletion of the internal repeating domain. .

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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