Mapping the prion protein using recombinant antibodies. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Mapping the prion protein using recombinant antibodies.

Dataset

identifier:	1293917
description:	epitope description:ENMYRYPNQVYY antigen name:Major prion protein host organism:Mus musculus PrP null antibody name:R72
aggregation:	instance of dataset
availability:	available
primaryPublications:	9765500

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001856
landingPage:	http://www.iedb.org/assay/1293917

Publication

type:	Literature
publicationVenue:	J Virol
dates:	1998

Dimension

study type:	b cell assays
subject species:	Mus musculus

Person

fullName:	R A Williamson D Peretz C Pinilla H Ball R B Bastidas R Rozenshteyn R A Houghten S B Prusiner D R Burton

Data Type

method:	flow cytometry

Study

name:	Mapping the prion protein using recombinant antibodies.
description:	The peptide sequence is invariant in hamster, human and bovine PrP. Fab R72, which recognizes the epitope, does not bind to PrP^c on the surface of the mouse N2a neuroblastoma cell line or to Syrian hamster (SHa) PrP^c on the surface of transfected CHO cells.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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