Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein.

Title:

Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein.

Dataset

identifier:	1290967
description:	epitope description:RVAISTYTTSLGAGPVSISAVAVLAPHSVL antigen name:Capsid protein host organism:Pan troglodytes antibody name:HEV#4
aggregation:	instance of dataset
availability:	available
primaryPublications:	10823861

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001864
landingPage:	http://www.iedb.org/assay/1290967

Publication

type:	Literature
publicationVenue:	J Virol
dates:	2000

Dimension

study type:	b cell assays
subject species:	Hepatitis E virus SAR-55

Person

fullName:	D J Schofield J Glamann S U Emerson R H Purcell

Data Type

method:	surface plasmon resonance (SPR)

Study

name:	Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein.
description:	The epitope-specific monoclonal antibody against the ORF2 protein of the SAR-55 strain of hepatitis E virus was isolated by phage display from a cDNA library of Pan troglodytes gamma1/κ antibody genes. The affinity of the mAb for ORF2 was determined by BIAcore.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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