Monoclonal antibodies to the hypervariable region 1 of hepatitis C virus capture virus and inhibit virus adsorption to susceptible cells in vitro.

Title:

Monoclonal antibodies to the hypervariable region 1 of hepatitis C virus capture virus and inhibit virus adsorption to susceptible cells in vitro.

Dataset

identifier:	1311995
description:	epitope description:HTRVTGGVQG antigen name:Genome polyprotein host organism:Mus musculus C57BL/6 antibody name:30F1
aggregation:	instance of dataset
availability:	available
primaryPublications:	10753706

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001888
landingPage:	http://www.iedb.org/assay/1311995

Publication

type:	Literature
publicationVenue:	Virology
dates:	2000

Dimension

study type:	b cell assays
subject species:	Hepatitis C virus

Person

fullName:	Y H Zhou Y K Shimizu M Esumi

Data Type

method:	surface plasmon resonance (SPR)

Study

name:	Monoclonal antibodies to the hypervariable region 1 of hepatitis C virus capture virus and inhibit virus adsorption to susceptible cells in vitro.
description:	The antigen-binding properties of the mAb were examinedby biointeraction analysis using the BIACORE 2000Biosensor. The purified synthetic HVR1 31-mer peptide, to which a cysteine residue was added at the C-terminus, was immobilized on CM5 sensor chips by the use of the thiol coupling method.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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