Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein.

Title:

Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein.

Dataset

identifier:	1312393
description:	epitope description:D429, R441, E452, D454 antigen name:Spike glycoprotein host organism:Mus musculus BALB/c antibody name:12B11, 18C2
aggregation:	instance of dataset
availability:	available
primaryPublications:	16670317

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001324
landingPage:	http://www.iedb.org/assay/1312393

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2006

Dimension

study type:	b cell assays
subject species:	SARS coronavirus Tor2

Person

fullName:	Yuxian He Jingjing Li Wenhui Li Sara Lustigman Michael Farzan Shibo Jiang

Data Type

method:	ELISA

Study

name:	Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein.
description:	Epitope-specific monoclonal antibodies raised to the receptor binding domain (RBD) of SARS Tor2 spike protein cross-reacted with the RBD from two other strains of coronavirus infecting human (GD03) and civet (palm civet SARS-CoV).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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