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Title: An anthrax lethal factor-neutralizing monoclonal antibody protects rats before and after challenge with anthrax toxin.
identifier: 1312626
description:
epitope description:DSLSEEEKELLNRIQVDS + NAc(D1)
antigen name:Lethal factor
host organism:Mus musculus BALB/c
antibody name:5B13B1
aggregation:
instance of dataset
availability:
available
primaryPublications: 16177329
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001800
landingPage: http://www.iedb.org/assay/1312626
type:
Literature
publicationVenue:
Infect Immun
dates:
2005
study type: b cell assays
subject species: Bacillus anthracis
fullName:
Nam-Kyu Lim
Jung-Hwan Kim
Mee Sook Oh
Sangyoon Lee
Se-Yeon Kim
Keun-Soo Kim
Hyun-Jung Kang
Hyo Jeong Hong
Kyung-Soo Inn
method:
surface plasmon resonance (SPR)
name:
An anthrax lethal factor-neutralizing monoclonal antibody protects rats before and after challenge with anthrax toxin.
description:
The authors add a cysteine residue at the C-terminus of the epitope for coupling to KLH.
Monoclonal antibodies, previously shown to bind to the epitope, were tested for their afinity to Lethal Factor. Another antibody, 3C16C3, also binding to the epitope, gave similar results.

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