Crystal structure of a hydrophobic immunodominant antigenic site on hepatitis C virus core protein complexed to monoclonal antibody 19D9D6.

Title:

Crystal structure of a hydrophobic immunodominant antigenic site on hepatitis C virus core protein complexed to monoclonal antibody 19D9D6.

identifier:	1312630
description:	epitope description:QIVGGVYLL antigen name:Genome polyprotein host organism:Mus musculus BALB/c antibody name:19D9D6
aggregation:	instance of dataset
availability:	available
primaryPublications:	12574359

study type:	b cell assays
subject species:	Hepatitis C virus

fullName:	René e Mé nez Marc Bossus Bruno H Muller Geneviè ve Sibaï Pascal Dalbon Fré dé ric Ducancel Colette Jolivet-Reynaud Enrico A Stura

method:	antigen inhibition

name:	Crystal structure of a hydrophobic immunodominant antigenic site on hepatitis C virus core protein complexed to monoclonal antibody 19D9D6.
description:	A fragment of the source antigen that contains the epitope inhibited the binding of epitope-specific mAb 19D9D6 to a larger fragment of the antigen, HCV core 1-120, which was used as immunogen to generate 19D9D6.

name:	iedb
homePage:	http://www.iedb.org

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