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identifier: 1313076
description:
epitope description:AKAVYQQFVEFYEKVTGTDL
antigen name:Capsid protein VP1
host organism:Oryctolagus cuniculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 7684458
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001912
landingPage: http://www.iedb.org/assay/1313076
type:
Literature
publicationVenue:
J Virol
dates:
1993
study type: b cell assays
subject species: Human parvovirus B19
fullName:
T Saikawa
S Anderson
M Momoeda
S Kajigaya
N S Young
method:
western blot
name:
Neutralizing linear epitopes of B19 parvovirus cluster in the VP1 unique and VP1-VP2 junction regions.
description:
Multiple antigenic peptides were synthesized to correspond to sequences within the unique region of VP1; this sequence was selected because it had been shown to elicit neutralizing antibodies when presented as a fusion protein. One of two animals produced neutralizing antisera in an erythroid colony assay after MAP immunization. This animal's serum, after concentration, showed binding on immunoblots to VP1 but not to fusion protein VPF1encoding amino acids 1-94, and the second animal had no evidence of either binding or neutralizing activity.

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