Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1313398 |
| description: |
epitope description:FHYDRNNIAVGADESVVKEAHREVINSSTEGLLLNIDKDIRKILSGYIVEIEDTEGLKEVINDRYDMLNISSLRQDGKTFIDFKKYNDKLPLYISNPNYKVNVYAVTKENTIINPSENGDTSTNGIKKILIFSKKGYEIG
antigen name:Protective antigen
host organism:Mus musculus Swiss Webster
antibody name:anti-anthrax PA
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
16820183 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1001934 |
| landingPage: |
http://www.iedb.org/assay/1313398 |
| type: |
Literature
|
| publicationVenue: |
Virology
|
| dates: |
2006
|
| study type: | b cell assays |
| subject species: | Bacillus anthracis |
| fullName: |
Mary Ellen Smith
Martin Koser
Sa Xiao
Catherine Siler
James P McGettigan
Catherine Calkins
Roger J Pomerantz
Bernhard Dietzschold
Matthias J Schnell
|
| method: |
ELISA
|
| name: |
Rabies virus glycoprotein as a carrier for anthrax protective antigen.
|
| description: |
All mice primed with inactivated or live rabies virus (RV) particles displaying a chimeric RV G glycoprotein-anthrax PA D4 fusion protein produced anthrax PA-specific antibodies, and the titers increased 10-fold after a second inoculation. A dose-response analysis showed a strong response to anthrax PA after immunization with 50 µg-50 ng of inactived RV displaying D4 that increased after a second inoculation. A dose of 5 ng also resulted in PA-specific seroconversion. Subclass IgG1 anti-PA antibodies were predominant over IgG2a, suggesting a Th2-biased response.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
