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Title: Induction of hepatitis C virus E1 envelope protein-specific immune response can be enhanced by mutation of N-glycosylation sites.
identifier: 1314151
description:
epitope description:YEVRNVSGMYHVTNDCSNSSIVYEAADMIMHTPGC
antigen name:Genome polyprotein
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 11711599
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001969
landingPage: http://www.iedb.org/assay/1314151
type:
Literature
publicationVenue:
J Virol
dates:
2001
study type: b cell assays
subject species: Hepatitis C virus
fullName:
A Fournillier
C Wychowski
D Boucreux
T F Baumert
J C Meunier
D Jacobs
S Muguet
E Depla
G Inchauspé
method:
ELISA
name:
Induction of hepatitis C virus E1 envelope protein-specific immune response can be enhanced by mutation of N-glycosylation sites.
description:
Sera from mice immunized with substitution mutants of the source protein (E1) (at several N-glycosylation sites) reacted positively with the epitope (peptide) by ELISA; sera from mice immunized with the N4 mutant were the most reactive.

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