DNA-based selection and screening of peptide ligands. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

DNA-based selection and screening of peptide ligands.

Dataset

identifier:	1317375
description:	epitope description:YTLPRSSNS host organism:Homo sapiens antibody name:HCV-positive sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	9831038

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002024
landingPage:	http://www.iedb.org/assay/1317375

Publication

type:	Literature
publicationVenue:	Nat Biotechnol
dates:	1998

Dimension

study type:	b cell assays
subject species:

Person

fullName:	F Bartoli M Nuzzo L Urbanelli F Bellintani C Prezzi R Cortese P Monaci

Data Type

method:	phage display

Study

name:	DNA-based selection and screening of peptide ligands.
description:	HCV-positive sera (4 of 16) reacted with the epitope selected from a random peptide library displayed on phage. No HCV-negative sera (16 of 16) reacted with the epitope. The epitope is among a group of HCV-specific phage-displayed peptides with homology to residues 35-44 (YLLPRRGPRL) of HCV core protein.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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