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Title: Improved reactivity of hepatitis C virus core protein epitopes in a conformational antigen-presenting system.
identifier: 1317427
description:
epitope description:MSTNPKPQRKTKRNTNRRPQ
antigen name:Genome polyprotein
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 9067642
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002053
landingPage: http://www.iedb.org/assay/1317427
type:
Literature
publicationVenue:
Clin Diagn Lab Immunol
dates:
1997
study type: b cell assays
subject species: Hepatitis C virus
fullName:
E Buratti
M Di Michele
P Song
C Monti-Bragadin
E A Scodeller
F E Baralle
S G Tisminetzky
method:
ELISA
name:
Improved reactivity of hepatitis C virus core protein epitopes in a conformational antigen-presenting system.
description:
This peptide was found to be highly reactive when assayed alone bound to the solid phase. The peptide was also inserted in a conformation-specific manner on the surface of the Flock House virus (FHV) capsid protein (I2 position). The goal of this sytem is to mimic the native antigenic conformation. Similar reactivity was seen in the FHV capsid, suggesting low conformational requirements for the epitope.

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