Prevention of hepatitis C virus infection in a chimpanzee by vaccination and epitope mapping of antiserum directed against hypervariable region 1.

Title:

Prevention of hepatitis C virus infection in a chimpanzee by vaccination and epitope mapping of antiserum directed against hypervariable region 1.

Dataset

identifier:	1317970
description:	epitope description:GGVQGHVTST antigen name:Genome polyprotein host organism:Pan troglodytes
aggregation:	instance of dataset
availability:	available
primaryPublications:	11251310

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001710
landingPage:	http://www.iedb.org/assay/1317970

Publication

type:	Literature
publicationVenue:	Hepatol Res
dates:	2001

Dimension

study type:	b cell assays
subject species:	Hepatitis C virus

Person

fullName:	J Goto S Nishimura M Esumi K Makizumi T Rikihisa T Nishihara K Mizuno Y -H. Zhou T Shikata S Fujiyama K

Data Type

method:	antigen inhibition

Study

name:	Prevention of hepatitis C virus infection in a chimpanzee by vaccination and epitope mapping of antiserum directed against hypervariable region 1.
description:	Pre-incubation of serum from the immunized animal with the paptide (GGVQGHVTST) did not inhibit anitibody binding to the fragment of source antigen, suggesting that this peptide is not immunogenic or antigenic.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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