Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1001841 |
| landingPage: |
http://www.iedb.org/assay/1319323 |
| type: |
Literature
|
| publicationVenue: |
J Virol
|
| dates: |
1997
|
| study type: | b cell assays |
| subject species: | Hepatitis C virus subtype 1b AD78 |
| fullName: |
A Zibert
W Kraas
H Meisel
G Jung
M Roggendorf
|
| method: |
ELISA
|
| name: |
Epitope mapping of antibodies directed against hypervariable region 1 in acute self-limiting and chronic infections due to hepatitis C virus.
|
| description: |
The peptide represents the hypervariable region 1 of a minor HCV-AD78 variant.
This peptide represents a minor variant of hypervariable region 1 of isolate HCV-AD78. Reactivity was determined using sera from patients infected with HCV-AD78 who developed chronic infections. The peptide was recognized with the same frequency in acutely-infected patients. Further epitope mapping using overlapping peptides spanning this peptide was also performed and antibodies were found to be directed mainly against the C-terminus of this peptide. Similar reactivity patterns were found in chronically infected patients not affected by the HCV-AD78 outbreak.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
