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Title: Characterization of monoclonal antibodies and epitope mapping of the NS4 protein of hepatitis C virus.
identifier: 1320301
description:
epitope description:SHLPYIEQGMQLAEQF
antigen name:Genome polyprotein
host organism:Homo sapiens
antibody name:anti-HCV positive patient serum
aggregation:
instance of dataset
availability:
available
primaryPublications: 12095709
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001922
landingPage: http://www.iedb.org/assay/1320301
type:
Literature
publicationVenue:
Immunol Lett
dates:
2002
study type: b cell assays
subject species: Hepatitis C virus subtype 1b
fullName:
O V Masalova
E I Lakina
A G Abdulmedzhidova
S N Atanadze
Yu A Semiletov
T V Shkurko
A N Burkov
T I Ulanova
V K Pimenov
V V Novikov
Yu E Khudyakov
H Fields
A A Kushch
method:
cross blocking
name:
Characterization of monoclonal antibodies and epitope mapping of the NS4 protein of hepatitis C virus.
description:
The sequence is from the NS4 protein.
MAb 1D11, which recognizes the epitope, competed with anti-HCV positive patient sera for binding to rNS4. MAb 1D11 binding to rNS4 was inhibited 75-100% by three sera, 50-74% by three sera, and 25-49% by three sera.

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