| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1002071 |
| landingPage: |
http://www.iedb.org/assay/1323640 |
| type: |
Literature
|
| publicationVenue: |
J Gen Virol
|
| dates: |
1996
|
| study type: | b cell assays |
| subject species: | Hepatitis C virus subtype 1a |
| fullName: |
M Sä
llberg
Z X Zhang
M Chen
L Jin
A Birkett
D L Peterson
D R Milich
|
| method: |
ELISA
|
| name: |
Immunogenicity and antigenicity of the ATPase/helicase domain of the hepatitis C virus non-structural 3 protein.
|
| description: |
The sequence is from the NS3 protein.
Sera from NS3-immunized mice reacted with rNS3 (1207-1612) but did not react significantly with the epitope. Low level antibody reactivity to a panel of 40 overlapping 16-mer peptides spanning residues 1207-1612 of HCV NS3 protein was observed in H-2 congenic B10 mice, leading the authors to conclude that the antigenic determinants were predominantly discontinuous or dependent on conformation.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |