| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1002087 |
| landingPage: |
http://www.iedb.org/assay/1324188 |
| type: |
Literature
|
| publicationVenue: |
Hepatology
|
| dates: |
1996
|
| study type: | b cell assays |
| subject species: | Hepatitis C virus |
| fullName: |
M Lechmann
H G Ihlenfeldt
I Braunschweiger
G Giers
G Jung
B Matz
R Kaiser
T Sauerbruch
U Spengler
|
| method: |
ELISA
|
| name: |
T- and B-cell responses to different hepatitis C virus antigens in patients with chronic hepatitis C infection and in healthy anti-hepatitis C virus--positive blood donors without viremia.
|
| description: |
Subjects with strong T cell responses had low or no detectable levels of peptide-specific antibodies, and vice-versa. In general, T cell responses were more common in patients who recovered from HCV infection, while B cell responses were more common in chronically infected patients. Therefore, the authors suggests that a benign course of HCV infection may be the consequence of the effective activation of T-helper lymphocytes.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |