Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M protein.

Title:

Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M protein.

Dataset

identifier:	1324291
description:	epitope description:DNGKAIYERARERALQELGPC antigen name:UniProt:A2RGM0 host organism:Mus musculus B10.BR
aggregation:	instance of dataset
availability:	available
primaryPublications:	16826479

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002089
landingPage:	http://www.iedb.org/assay/1324291

Publication

type:	Literature
publicationVenue:	J Infect Dis
dates:	2006

Dimension

study type:	b cell assays
subject species:	Streptococcus sp. 'group A'

Person

fullName:	Colleen Olive Hsien Kuo Sun Mei-Fong Ho Joanne Dyer Aniko Horvá th Istvan Toth Michael F Good

Data Type

method:	ELISA

Study

name:	Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M protein.
description:	A low level of IgG specific for another group A streptococcus epitope (J8) was detected in sera from mice immunized with the epitope. Levels of salivary IgA were undetectable.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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