Enhancing the immunogenicity and modulating the fine epitope recognition of antisera to a helical group A streptococcal peptide vaccine candidate from the M protein using lipid-core peptide technology.

Title:

Dataset

identifier:	1325917
description:	epitope description:ASREAKKQVEKALE antigen name:UniProt:A2RGM0 host organism:Mus musculus B10.BR
aggregation:	instance of dataset
availability:	available
primaryPublications:	11940119

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001844
landingPage:	http://www.iedb.org/assay/1325917

Publication

type:	Literature
publicationVenue:	Immunol Cell Biol
dates:	2002

Dimension

study type:	b cell assays
subject species:	Streptococcus pyogenes

Person

fullName:	Wendy A Hayman Istvan Toth Nicholas Flinn Martin Scanlon Michael F Good

Data Type

method:	biological activity

Study

name:	Enhancing the immunogenicity and modulating the fine epitope recognition of antisera to a helical group A streptococcal peptide vaccine candidate from the M protein using lipid-core peptide technology.
description:	Antisera from mice immunized with a fragment of the source antigen containing the epitope displayed opsonic activity against M6 group A streptococci; mice were immunized with either the fragment or the fragment contained within a lipid core peptide construct. Immunization with the fragment alone resulted in weak opsonic activity of the resulting antisera; immunization with the fragment contained in a lipid core construct gave much higher opsonic activity.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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