Confirmation of cross-reactivity between Lyme antibody H9724 and human heat shock protein 60 by a combinatorial approach.

Title:

Confirmation of cross-reactivity between Lyme antibody H9724 and human heat shock protein 60 by a combinatorial approach.

identifier:	1326145
description:	epitope description:MLQGVD + NAc(M1) antigen name:60 kDa heat shock protein, mitochondrial (UniProt:P10809) host organism:Mus musculus antibody name:H9724
aggregation:	instance of dataset
availability:	available
primaryPublications:	9375512

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Z Yu J Tu Y H Chu

method:	antigen inhibition

name:	Confirmation of cross-reactivity between Lyme antibody H9724 and human heat shock protein 60 by a combinatorial approach.
description:	The mimotope inhibited the binding of the mAb H9724 (specific for a Borrelia burgdorferi flagellin epitope, EGVQQEGAQQPA ) to the peptide Ac-VQQEGAXXRM (Ac = acetylation, X = Β-alanine) with an IC50 of 25 uM.

name:	iedb
homePage:	http://www.iedb.org

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