Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Antigenicity of chimeric and cyclic synthetic peptides based on nonstructural proteins of GBV-C/HGV. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1002142 |
| landingPage: |
http://www.iedb.org/assay/1326389 |
| type: |
Literature
|
| publicationVenue: |
J Pept Sci
|
| dates: |
2006
|
| study type: | b cell assays |
| subject species: | Hepatitis C virus |
| fullName: |
T Pé
rez
G Ercilla
W C Chan
I Haro
|
| method: |
ELISA
|
| name: |
Antigenicity of chimeric and cyclic synthetic peptides based on nonstructural proteins of GBV-C/HGV.
|
| description: |
Two epitopes and a triglycyl spacer between them were synthesized resulting in NS5a(112-126)GGG NS4b(8-22) chimeric peptide.
35 samples of the hemodialyzed patients were tested for the presence of anti-HGV E2 protein as an indication of recovery from HGV. 11 patients tested positive and 24 tested negative by ELISA. 4 out of 11 (36%) and 10 out of 24 (41%) tested positive when the epitope was used as antigen.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |