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identifier: 1327097
description:
epitope description:EVLTRRQSQDPKYVTQRIS
antigen name:UniProt:A2RGM0
host organism:Mus musculus B10.BR
aggregation:
instance of dataset
availability:
available
primaryPublications: 16703510
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002168
landingPage: http://www.iedb.org/assay/1327097
type:
Literature
publicationVenue:
J Infect Dis
dates:
2006
study type: b cell assays
subject species: Streptococcus pyogenes
fullName:
Colleen Olive
Mei-Fong Ho
Joanne Dyer
Douglas Lincoln
Nadia Barozzi
Istvan Toth
Michael F Good
method:
ELISA
name:
Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcus.
description:
Lower titters were observed for epitope-specific antibody responses from the mice immunized with tetraepitopic lipid core peptide (LCP) construct without adjuvant CFA. A decrease of titer was observed over time after the immunization. Increased the number of epitopes attached to LCP limited effectiveness of some epitopes, while mixing different LCP constructs had no adverse effect.

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