Disease-associated prion protein elicits immunoglobulin M responses in vivo. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Disease-associated prion protein elicits immunoglobulin M responses in vivo.

Dataset

identifier:	1327615
description:	epitope description:GGGTHNQWNKPSKPKTNLKH antigen name:Major prion protein host organism:Mus musculus FVB/N Prp null antibody name:ICSM 35
aggregation:	instance of dataset
availability:	available
primaryPublications:	15706401

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002195
landingPage:	http://www.iedb.org/assay/1327615

Publication

type:	Literature
publicationVenue:	Mol Med
dates:	2004

Dimension

study type:	b cell assays
subject species:	Mus musculus

Person

fullName:	Mourad Tayebi Perry Enever Zahid Sattar John Collinge Simon Hawke

Data Type

method:	immunoprecipitation

Study

name:	Disease-associated prion protein elicits immunoglobulin M responses in vivo.
description:	MAb ICSM 35 immunoprecipitates PrP^sc from RML scrapie-infected mouse brain homogenates and PrP^c from normal mouse brain homogenates. MAb ICSM 35 also binds PrP^sc from proteinase K-treated from RML-infected brain homogenates.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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