Human antibodies to the polymorphic block 2 domain of the Plasmodium falciparum merozoite surface protein 1 (MSP-1) exhibit a highly skewed, peptide-specific light chain distribution.

Title:

Human antibodies to the polymorphic block 2 domain of the Plasmodium falciparum merozoite surface protein 1 (MSP-1) exhibit a highly skewed, peptide-specific light chain distribution.

Dataset

identifier:	1332574
description:	epitope description:KNQLAGKDEYEAKQKEAE antigen name:Heat shock 70 kDa protein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	16033534

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002259
landingPage:	http://www.iedb.org/assay/1332574

Publication

type:	Literature
publicationVenue:	Immunol Cell Biol
dates:	2005

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum

Person

fullName:	Hé lè ne Jouin Olivier Garraud Shirley Longacre Franç oise Baleux Odile Mercereau-Puijalon Geneviè ve Milon

Data Type

method:	ELISA

Study

name:	Human antibodies to the polymorphic block 2 domain of the Plasmodium falciparum merozoite surface protein 1 (MSP-1) exhibit a highly skewed, peptide-specific light chain distribution.
description:	The light-chain kappa/lambda distribution of peptide-specific antibody responses was examined in healthy Senegalese individuals with no history of clinical malaria during the previous 6 months. The response involved predominantly the kappa light chain isotype.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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