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Title: The most polymorphic residue on Plasmodium falciparum apical membrane antigen 1 determines binding of an invasion-inhibitory antibody.
identifier: 1332580
description:
epitope description:E189
antigen name:Apical membrane antigen 1
host organism:Mus musculus
antibody name:1F9
aggregation:
instance of dataset
availability:
available
primaryPublications: 16622199
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002244
landingPage: http://www.iedb.org/assay/1332580
type:
Literature
publicationVenue:
Infect Immun
dates:
2006
study type: b cell assays
subject species: Plasmodium falciparum 3D7
fullName:
A M Coley
K Parisi
R Masciantonio
J Hoeck
J L Casey
V J Murphy
K S Harris
A H Batchelor
R F Anders
M Foley
method:
biological activity
name:
The most polymorphic residue on Plasmodium falciparum apical membrane antigen 1 determines binding of an invasion-inhibitory antibody.
description:
The epitope specific mAb 1F9 inhibited invasion of strain-specific (3D7) parasites to red blood cells, as well as bound to the strain-specific protein (both strains 3D7 and D10) and the fragment (aa 179-247) on immunoblot and ELISA under non-reducing condition.

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