Identification of a major B-cell epitope of the Plasmodium falciparum glutamate-rich protein (GLURP), targeted by human antibodies mediating parasite killing.

Title:

Identification of a major B-cell epitope of the Plasmodium falciparum glutamate-rich protein (GLURP), targeted by human antibodies mediating parasite killing.

Dataset

identifier:	1336018
description:	epitope description:EIILPENVETEEIIDDVPSPKHSNHETF antigen name:Glutamate-rich protein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	10930674

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002476
landingPage:	http://www.iedb.org/assay/1336018

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	2000

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum

Person

fullName:	M Theisen S Soe S G Jessing L M Okkels S Danielsen C Oeuvray P Druilhe S Jepsen

Data Type

method:	ELISA

Study

name:	Identification of a major B-cell epitope of the Plasmodium falciparum glutamate-rich protein (GLURP), targeted by human antibodies mediating parasite killing.
description:	Plasma from 23 out of 79 clinically immune individuals recognized the epitope by ELISA. Affinity purification from 4 of these plasma samples revealed the IgG subclass content of the anti-epitope antibodies to be predominantly IgG1 and IgG3.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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