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identifier: 1336101
description:
epitope description:IKND
antigen name:Erythrocyte membrane protein 1, PfEMP1 (UniProt:Q8IBW8)
host organism:Mus musculus
antibody name:M26-32
aggregation:
instance of dataset
availability:
available
primaryPublications: 1723149
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002496
landingPage: http://www.iedb.org/assay/1336101
type:
Literature
publicationVenue:
Mol Biochem Parasitol
dates:
1991
study type: b cell assays
subject species: Plasmodium falciparum FCR-3/Gambia
fullName:
Q Cheng
G Jones
E X Liu
C Kidson
A Saul
method:
phage display
name:
Identification of a common Plasmodium epitope (CPE) recognised by a pan-specific inhibitory monoclonal antibody.
description:
The epitope has also been identified in the DHFR-TS protein of P. chabaudi.
A P. falciparum Malayan CAMP genomic DNA expression library was screened with the monoclonal antibody, and four positive clones expressing the epitope were selected. The monoclonal antibody has previously been shown to inhibit P. falciparum growth and block the invasion of merozoites in culture.

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