| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1002496 |
| landingPage: |
http://www.iedb.org/assay/1336101 |
| type: |
Literature
|
| publicationVenue: |
Mol Biochem Parasitol
|
| dates: |
1991
|
| study type: | b cell assays |
| subject species: | Plasmodium falciparum FCR-3/Gambia |
| fullName: |
Q Cheng
G Jones
E X Liu
C Kidson
A Saul
|
| method: |
phage display
|
| name: |
Identification of a common Plasmodium epitope (CPE) recognised by a pan-specific inhibitory monoclonal antibody.
|
| description: |
The epitope has also been identified in the DHFR-TS protein of P. chabaudi.
A P. falciparum Malayan CAMP genomic DNA expression library was screened with the monoclonal antibody, and four positive clones expressing the epitope were selected. The monoclonal antibody has previously been shown to inhibit P. falciparum growth and block the invasion of merozoites in culture.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |