Peptides inducing short-lived antibody responses against Plasmodium falciparum malaria have shorter structures and are read in a different MHC II functional register.

Title:

Peptides inducing short-lived antibody responses against Plasmodium falciparum malaria have shorter structures and are read in a different MHC II functional register.

Dataset

identifier:	1333026
description:	epitope description:LKMTNNAISFMSISASLEKK host organism:Aotus nancymaae
aggregation:	instance of dataset
availability:	available
primaryPublications:	15865420

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002270
landingPage:	http://www.iedb.org/assay/1333026

Publication

type:	Literature
publicationVenue:	Biochemistry
dates:	2005

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Manuel E Patarroyo Martha P Alba Luis E Vargas Yolanda Silva Jaiver Rosas Raú l Rodrí guez

Data Type

method:	in vivo assay

Study

name:	Peptides inducing short-lived antibody responses against Plasmodium falciparum malaria have shorter structures and are read in a different MHC II functional register.
description:	This analog peptide is derived from the high-activity binding peptide 6725 from Plasmodium falciparum. Immunized monkeys were challenged 20 days after the last peptide boost with i.v. inoculation of 200,000 RBC infected with strain FVO of P. falciparum (100% infective). Protection was defined as the complete absence of parasites in the monkey blood throughout the 15 days following challenge.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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