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Title: A conserved peptide sequence of the Plasmodium falciparum circumsporozoite protein and antipeptide antibodies inhibit Plasmodium berghei sporozoite invasion of Hep-G2 cells and protect immunized mice against P. berghei sporozoite challenge.
identifier: 1335350
description:
epitope description:IEQYLKKIKNSISTEWSPCSVTCGNGIQVRIK
antigen name:Circumsporozoite (CS) protein
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 7591073
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002388
landingPage: http://www.iedb.org/assay/1335350
type:
Literature
publicationVenue:
Infect Immun
dates:
1995
study type: b cell assays
subject species: Plasmodium falciparum
fullName:
S Chatterjee
M Wery
P Sharma
V S Chauhan
method:
ELISA
name:
A conserved peptide sequence of the Plasmodium falciparum circumsporozoite protein and antipeptide antibodies inhibit Plasmodium berghei sporozoite invasion of Hep-G2 cells and protect immunized mice against P. berghei sporozoite challenge.
description:
Sera from the peptide immunized mice were assayed for reactivity with the peptide. This peptide was also shown to significantly inhibit P. berghei sporozoite invasion into Hep-G2 cells when co-incubated with the sporozoites in vitro.

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