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identifier: 1335388
description:
epitope description:RRKAHAGNKKAEDLTMDDLE
antigen name:Circumsporozoite (CS) protein
host organism:Oryctolagus cuniculus New Zealand White
antibody name:rabbit anti-C2
aggregation:
instance of dataset
availability:
available
primaryPublications: 2580025
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002401
landingPage: http://www.iedb.org/assay/1335388
type:
Literature
publicationVenue:
J Immunol
dates:
1985
study type: b cell assays
subject species: Plasmodium knowlesi strain H
fullName:
U Vergara
A Ruiz
A Ferreira
R S Nussenzweig
V Nussenzweig
method:
in vivo assay
name:
Conserved group-specific epitopes of the circumsporozoite proteins revealed by antibodies to synthetic peptides.
description:
Rabbit antibodies to the epitope did not neutralize the infectivity of sporozoites from a heterologous species, P. berghei. A/J mice were injected i.v. with 5 x 10^3 sporozoites that were pre-incubated with rabbit anti-N2 or normal rabbit serum. Mice were monitored daily for the presence of blood stages of the parasite.

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