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Title: Pan DR binding sequence provides T-cell help for induction of protective antibodies against Plasmodium yoelii sporozoites.
identifier: 1335763
description:
epitope description:QGPGAP
antigen name:Circumsporozoite protein (UniProt:Q7RJT9)
host organism:Mus musculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 10195633
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002395
landingPage: http://www.iedb.org/assay/1335763
type:
Literature
publicationVenue:
Vaccine
dates:
1999
study type: b cell assays
subject species: Plasmodium yoelii yoelii
fullName:
E D Franke
S L Hoffman
J B Sacci Jr
R Wang
Y Charoenvit
E Appella
R Chesnut
J Alexander
M F Del Guercio
A Sette
method:
biological activity
name:
Pan DR binding sequence provides T-cell help for induction of protective antibodies against Plasmodium yoelii sporozoites.
description:
Mice immunized with epitope with or without Pan-DR epitope (PADRE, sequence is aKXVAAWTLKAa) were able to inhibit liver stage development of P yoelii in mouse hepatocytes.

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