Circumsporozoite protein of Plasmodium berghei: gene cloning and identification of the immunodominant epitopes.

Title:

Circumsporozoite protein of Plasmodium berghei: gene cloning and identification of the immunodominant epitopes.

identifier:	1335815
description:	epitope description:DPAPPNANDPAPPNAND antigen name:Circumsporozoite (CS) protein, putative host organism:Mus musculus antibody name:3D11
aggregation:	instance of dataset
availability:	available
primaryPublications:	2432395

study type:	b cell assays
subject species:	Plasmodium berghei

fullName:	D J Eichinger D E Arnot J P Tam V Nussenzweig V Enea

method:	antigen inhibition

name:	Circumsporozoite protein of Plasmodium berghei: gene cloning and identification of the immunodominant epitopes.
description:	The sequence is a dimer of a repeat unit from the first repeat region in the circumsporozoite protein. The epitope inhibited the binding of mAb 3D11 to extracts of P. berghei sporozoites, but required a 1000-fold higher concentration to achieve the same inhibition obtained with peptides NG16 (NDPPPPNPNDPAPPQG) or DD17(1) (DPPPPNPNDPPPPNPND).

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.