Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.

Dataset

identifier:	1339347
description:	epitope description:QGPGAPQGPGAP antigen name:Circumsporozoite protein (UniProt:Q7RJT9) host organism:Mus musculus BALB/cByJ
aggregation:	instance of dataset
availability:	available
primaryPublications:	7937907

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002729
landingPage:	http://www.iedb.org/assay/1339347

Publication

type:	Literature
publicationVenue:	Proc Natl Acad Sci U S A
dates:	1994

Dimension

study type:	b cell assays
subject species:	Plasmodium yoelii

Person

fullName:	M Sedegah R Hedstrom P Hobart S L Hoffman

Data Type

method:	ELISA

Study

name:	Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.
description:	Sera from mice immunized with plasmid DNA had >10times the level of antibodies to sporozoites as did mice immunized with irradiated sporozoites, but had similar levels ofantibodies against the peptide by ELISA.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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