Absence of antigenic diversity in Pf155, a major parasite antigen in membranes of erythrocytes infected with Plasmodium falciparum.

Title:

Absence of antigenic diversity in Pf155, a major parasite antigen in membranes of erythrocytes infected with Plasmodium falciparum.

identifier:	1336655
description:	epitope description:EENVEHDA antigen name:DNAJ protein, putative host organism:Mus musculus antibody name:MoMAb anti-EENVEHDA
aggregation:	instance of dataset
availability:	available
primaryPublications:	2448335

study type:	b cell assays
subject species:	Plasmodium falciparum FC27/Papua New Guinea

fullName:	H K Perlmann K Berzins B Wå hlin R Udomsangpetch W Ruangjirachuporn M Wahlgren P H Perlmann

method:	western blot

name:	Absence of antigenic diversity in Pf155, a major parasite antigen in membranes of erythrocytes infected with Plasmodium falciparum.
description:	The C-terminal end of the ring-infected erythrocyte surface antigen (RESA Pf155) contains multiple tandem repeats of the epitope. A mouse mAb, raised against the epitope, immunoblotted Pf155 from merozoite-enriched lysates from strains F32 (Tanzania), IMTM22/7G8 (Brazil), or Thai1 (Thailand). The authors show that Pf155 in lysates from all three strains is similar in size and antigenicity, and conclude that Pf155 is antigenically invariant.

name:	iedb
homePage:	http://www.iedb.org

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