Antibodies to a conserved-motif peptide sequence of the Plasmodium falciparum thrombospondin-related anonymous protein and circumsporozoite protein recognize a 78-kilodalton protein in the asexual blood stages of the parasite and inhibit merozoite invasion in vitro.

Title:

Dataset

identifier:	1336761
description:	epitope description:WSPCSVTCG antigen name:Thrombospondin-related anonymous protein, TRAP host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	8675323

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002542
landingPage:	http://www.iedb.org/assay/1336761

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	1996

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum

Person

fullName:	P Sharma A Bharadwaj V K Bhasin V N Sailaja V S Chauhan

Data Type

method:	biological activity

Study

name:	Antibodies to a conserved-motif peptide sequence of the Plasmodium falciparum thrombospondin-related anonymous protein and circumsporozoite protein recognize a 78-kilodalton protein in the asexual blood stages of the parasite and inhibit merozoite invasion in vitro.
description:	Antisera to the epitope was able to inhibit the in vitro growth of Plasmodium falciparum and the in vitro infectivity of erythrocytes.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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