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Title: A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts.
identifier: 1337479
description:
epitope description:NANPNANPNANP
antigen name:Circumsporozoite (CS) protein
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 12438363
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002525
landingPage: http://www.iedb.org/assay/1337479
type:
Literature
publicationVenue:
Infect Immun
dates:
2002
study type: b cell assays
subject species: Plasmodium falciparum
fullName:
A Birkett
K Lyons
A Schmidt
D Boyd
G A Oliveira
A Siddique
R Nussenzweig
J M Calvo-Calle
E Nardin
method:
ELISA
name:
A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts.
description:
Antibodies against CS repeat were obtained just one dose of immunization with high levels of specific IgG1 and IgG3. There were increased Ab titters and all other IgG subclasses after second and third dose.

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