Efficacy of murine malaria sporozoite vaccines: implications for human vaccine development. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Efficacy of murine malaria sporozoite vaccines: implications for human vaccine development.

Dataset

identifier:	1337003
description:	epitope description:DPAPPNANDPAPPNAN antigen name:Circumsporozoite (CS) protein, putative host organism:Mus musculus C57BL/6 antibody name:anti-(D-16-N)
aggregation:	instance of dataset
availability:	available
primaryPublications:	3551073

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002574
landingPage:	http://www.iedb.org/assay/1337003

Publication

type:	Literature
publicationVenue:	Science
dates:	1987

Dimension

study type:	b cell assays
subject species:	Plasmodium berghei

Person

fullName:	J E Egan J L Weber W R Ballou M R Hollingdale W R Majarian D M Gordon W L Maloy S L Hoffman R A Wirtz I Schneider

Data Type

method:	ELISA

Study

name:	Efficacy of murine malaria sporozoite vaccines: implications for human vaccine development.
description:	The circumsporozoite protein contains multiple tandem repeats of the sequence DPAPPNAN. Sera from mice immunized with the epitope bound to P. berghei NK65 sporozoites. The sera also blocked sporozoite invasion of human HepG16-2A hepatoma cells in vitro.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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