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Title: Structure of an immunodominant epitope of the circumsporozoite surface protein of Plasmodium knowlesi.
identifier: 1337721
description:
epitope description:QAQGDGANAGQPQAQGDGANAGQP
antigen name:Circumsporozoite (CS) protein
host organism:Mus musculus
antibody name:2G3, 5H8, 8B8, 8A8, 8E11, 6B8
aggregation:
instance of dataset
availability:
available
primaryPublications: 6210107
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002596
landingPage: http://www.iedb.org/assay/1337721
type:
Literature
publicationVenue:
Biochemistry
dates:
1984
study type: b cell assays
subject species: Plasmodium knowlesi strain H
fullName:
D H Schlesinger
A H Cochrane
R W Gwadz
G N Godson
R Melton
R S Nussenzweig
V Nussenzweig
method:
radio immuno assay (RIA)
name:
Structure of an immunodominant epitope of the circumsporozoite surface protein of Plasmodium knowlesi.
description:
The circumsporozoite protein contains multiple tandem repeats of the sequence NAGQPQAQGDGA.
Six mAbs (2G3, 5H8, 8B8, 8A8, 8E11, and 6B8) prepared against P. knowlesi sporozoites reacted with the epitope. Excess unlabeled epitope inhibited the binding of labeled epitope to each mAb coupled to beads.

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