Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion.

Title:

Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion.

Dataset

identifier:	1337843
description:	epitope description:SNNEYKVNEREDERTLTKEYEDIVLKSHMNRESDDGELYDEN antigen name:Erythrocyte binding antigen 175 host organism:Mus musculus BALB/c antibody name:anti-EBA-peptide 4
aggregation:	instance of dataset
availability:	available
primaryPublications:	2229177

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002609
landingPage:	http://www.iedb.org/assay/1337843

Publication

type:	Literature
publicationVenue:	J Cell Biol
dates:	1990

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum CAMP/Malaysia

Person

fullName:	B K Sim P A Orlandi J D Haynes F W Klotz J M Carter D Camus M E Zegans J D Chulay

Data Type

method:	immuno staining

Study

name:	Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion.
description:	The epitope sequence is predicted to contain an antigenic site based on its hydrophilicity index. Sera from mice immunized with the epitope immunostained the cytoplasm of merozoites in schiznonts and free merozoites, but did not stain ring-stage parasites.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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